publications

publications in reversed chronological order.

2023

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    Estimation of indirect genetic effects and heritability under assortative mating
    Alexander Strudwick Young
    bioRxiv, 2023
  2. Discovering genes that affect cognitive ability
    Alexander Strudwick Young, and Hilary C Martin
    Trends in Genetics, 2023

2022

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    Mendelian imputation of parental genotypes improves estimates of direct genetic effects
    Alexander Strudwick Young, Seyed Moeen Nehzati, Stefania Benonisdottir, and 7 more authors
    Nature genetics, 2022
  2. ea4_preview.png
    Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
    Aysu Okbay, Yeda Wu, Nancy Wang, and 8 more authors
    Nature genetics, 2022
  3. Discovering missing heritability in whole-genome sequencing data
    Alexander I Young
    Nature Genetics, 2022
  4. Novel estimators for family-based genome-wide association studies increase power and robustness
    Junming Guan, Seyed Moeen Nehzati, Daniel J Benjamin, and 1 more author
    bioRxiv, 2022
  5. Cross-trait assortative mating is widespread and inflates genetic correlation estimates
    Richard Border, Georgios Athanasiadis, Alfonso Buil, and 8 more authors
    Science, 2022

2021

  1. Resource profile and user guide of the Polygenic Index Repository
    Joel Becker, Casper AP Burik, Grant Goldman, and 8 more authors
    Nature human behaviour, 2021

2020

  1. How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa)
    Rosa Cheesman, Espen Moen Eilertsen, Yasmin I Ahmadzadeh, and 8 more authors
    BMC medicine, 2020
  2. Family analysis with Mendelian imputations
    Augustine Kong, Stefania Benonisdottir, and Alexander I Young
    BioRxiv, 2020

2019

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    Deconstructing the sources of genotype-phenotype associations in humans
    Alexander Strudwick Young, Stefania Benonisdottir, Molly Przeworski, and 1 more author
    Science, 2019
  2. solving.png
    Solving the missing heritability problem
    Alexander Strudwick Young
    PLoS genetics, 2019

2018

  1. RDR.png
    Relatedness disequilibrium regression estimates heritability without environmental bias
    Alexander Strudwick Young, Michael L Frigge, Daniel F Gudbjartsson, and 7 more authors
    Nature genetics, 2018
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    Identifying loci affecting trait variability and detecting interactions in genome-wide association studies
    Alexander Strudwick Young, Fabian L Wauthier, and Peter Donnelly
    Nature genetics, 2018
  3. The nature of nurture: effects of parental genotypes
    Augustine Kong, Gudmar Thorleifsson, Michael L Frigge, and 8 more authors
    Science, 2018

2017

  1. Selection against variants in the genome associated with educational attainment
    Augustine Kong, Michael L Frigge, Gudmar Thorleifsson, and 8 more authors
    Proceedings of the National Academy of Sciences, 2017

2016

  1. Powerful decomposition of complex traits in a diploid model
    Johan Hallin, Kaspar Märtens, Alexander I Young, and 5 more authors
    Nature Communications, 2016
  2. Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index
    Alexander I Young, Fabian Wauthier, and Peter Donnelly
    Nature communications, 2016
  3. Interactions in complex traits
    Alexander Young
    University of Oxford, 2016

2014

  1. Estimation of epistatic variance components and heritability in founder populations and crosses
    Alexander I Young, and Richard Durbin
    Genetics, 2014

2011

  1. Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects
    Stephen Gregory Addinall, Eva-Maria Holstein, Conor Lawless, and 8 more authors
    PLoS genetics, 2011

2010

  1. Colonyzer: automated quantification of micro-organism growth characteristics on solid agar
    Conor Lawless, Darren J Wilkinson, Alexander Young, and 2 more authors
    BMC bioinformatics, 2010